Core Facilities

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10 461LAS ANIMALS USED IN RESEARCH
95LAS ACTIVE PROCEDURES
223ESU ANIMALS USED IN RESEARCH
15ESU ACTIVE PROCEDURES
77PIP ACTIVE PROJECTS
1604BIOBANC NEW SAMPLE DONATIONS
33BIOBANC PROJECTS WHICH ASKED FOR SAMPLES
9240UAT SERVICES PERFORMED
48UAT USER GROUPS (INTERNAL GROUPS/EXTERNAL CLIENTS)
287USIC ACTIVE CLINICAL TRIALS/STUDIES
83USIC CLINICAL TRIALS/STUDIES PRINCIPAL INVESTIGATORS
258UEB NEW STATISTICS SERVICES
41UEB NEW BIOINFORMATICS SERVICES
59ARO ACTIVE STUDIES

INDEX

LAB ANIMAL SERVICE (LAS)

Animals Used in Research

9787MICE
674RATS
*Total number of mice and rats used for research purposes according to the spanish decree RD 53/2013 definition of experimental procedure.

Active producers per species

81MICE
14RATS
*Total number of experimental procedures approved by the Competent Authority (generalitat de Catalunya

Active procedures per area and species

Active procedures per area and species

Annual average of cages and individuals/week*

2820MICE
116RATS
*Average number of cages per week (maximum number of animals x cage =5)

EXPERIMENTAL SURGERY UNIT (ESU)

Animals used in Research
Rabbits 172
Sheep 26
Pigs 25
TOTAL 223

 

Active procedures per species
Rabbits 5
Sheep 4
Pigs 5
Ex vivo procedures 1
TOTAL 15

 

Active procedures per area and species**

Active procedures per area and species

TOTAL

5Rabbits
4Sheep
5Pigs

(**)Total number of experimental procedures approved by the Competent Authority (Generalitat de Catalunya).

PRECLINICAL IMAGING PLATAFORM ACTIVITY (PIP)

OPTICAL IMAGING

Research Groups Acquiring Hours Quantification Hours Research projects
VHIR 44 14 13
Translational Research in Child and Adolescent Cancer  4
Biomedical Research in Cancer Stem Cells 1
Liver Diseases 1
Functional Validation and Preclinical Research 5
Neurodegenerative Diseases 1
Neurovascular Diseases 1
VHIO 403.85 73.75 33
Gene expression and cancer laboratory 16
Mouse models of cancer therapies 6
Grow Factors 1
Cellular plasticity and cancer 3
Experimental hematology 3
Stem cells and cancer 2
Tumor biomarkers 2
External users 77 31.50 4
Total hours 525 119 50

MICROCT

Research Groups Studies (acquisition and analysis) Research projects
VHIR 280 5
Nephrology 1
Pneumology 1
Pharmacokinetic nanoparticles 1
Medical Imaging and Metabolism 2
VHIO 728 12
Mouse models of cancer therapies 11
Stem cells and cancer 1
External users 898 2
Total acquisitions 1 906 19

ULTRASOUND

Research Groups Studies (acquisition and analysis) Research projects
VHIR 9 3
Malalties inmunomediades i terapies innovadores 1
Neuromuscular and Mitochondrial Pathology 1
Bioengineering, Cell therapy and surgery in congenital malformations 1
VHIO 68 4
Experimental hematology 1
Grow Factors 1
Chromatin Dynamics in Cancer Group 1
Stem cells and cancer 1
External users 568 1
Total acquisitions 645 8

BIOBANK

NUMBER OF NEW SAMPLE DONATIONS

1604TOTAL
Cardiology Bank 168
Digestive Pathologies Bank 4
IMID: Immune Mediated Inflammatory Diseases 217
Immunology Bank 90
Nephrology Bank 223
Neurodegenerative Pathologies Bank 27
Neurological Tissue Bank 10
Obesity Bank 60
Pulmonar Bank 325
Tumor Bank 368
Others 112

Number of Projects which have asked for sample processing services

Number of Projects which have asked for sample processing services
9CARDIOLOGY BANK
1DIGESTIVE PATHOLOGIES BANK
1IMID: IMMUNE MEDIATED INFLAMMATORY DISEASES
4IMMUNOLOGY BANK
4NEPHROLOGY BANK
1NEUROLOGICAL TISSUE BANK
2OBESITY BANK
3PULMONARY BANK
2TUMOR BANK
10OTHERS

Number of Projects which have asked for samples (Material Transfer Service)

Number of Projects which have asked for samples (Material Transfer Service)
4CARDIOLOGY BANK
1DIGESTIVE PATHOLOGIES BANK
6IMID: IMMUNE MEDIATED INFLAMMATORY DISEASES
8IMMUNOLOGY BANK
1NEUROLOGICAL TISSUE BANK
1OBESITY BANK
2SEPSIS BANK
5TUMOR BANK
5OTHERS

 

UAT (High Technology Unit)

User groups

User groups
40VHIR
2PARTNER INSTITUTIONS
3PUBLIC RESEARCH ORGANIZATIONS
3PRIVATE CLIENTS

Number of services performed*

Number of services performed
423MOLECULAR DIAGNOSIS
4508GENOMICS
2170MICROSCOPY
1521CYTOMICS
619METABOLOMICS
(*) The number of services for each platform is calculated by adding the number of units performed by each individual service within a platform. Internal and outsourced services managed by UAT are included.

Internal projects supported

Nº of supported projects
Competitive funded projects 100
Non-competitive funded projects 36

% of service requests (**)

service requests
73.53%Competitive funded projects
26.47%Non-competitive funded projects
(**) Calculated over the total number of service requests charged to internal projects.

% of total income (***)

total income
79.12%Competitive funded projects
20.88%Non-competitive funded projects
(***) Calculated over the UAT total income for fees charged to internal projects.

New internal services

PLATFORM SERVICE
Microscopy Acquisition and start-up of a new widefield, multidimensional microscope adapted for in vivo experiments (Thunder Imager Live Cell&3D system)
Microscopy Confocal adquisition below optical resolution (120x120x140 nm) using the Airyscan detector of the Zeiss LSM980 microscope
Microscopy Mosaic adquistion in live and fixed samples using the Zeiss LSM980 and Leica Thunder microscopes
Genomics Mouse genotyping
Metabolomics Development of different methods for detection and quantification of various endogenous metabolites and drugs in biological matrixes

USIC-HEALTHCARE PLATFORM

Active clinical trials/studies 287
Services/Units of HUVH 33
No. principal investigators 83
No. of visits 3 545
No. intravenous treatments 154
No. spaces used for monitoring/auditories/center selection visits, start-up and close-out visits 573
% clinical trials USIC-Healthcare Area/ active clinical trials in HUVH 21.8%
% of the use of healthcare spaces 35.2%
Request of studies for medical consultation 211
Request of studies for day hospital 30
Request of studies for support of research nurse 171
Petitions of public funded studies 42
Petitions of private funded studies 245

UEB (Statistics & Bioinformatics Unit)

UEB services by type

TOTAL (€) TOTAL (hours) TOTAL (# Services) NUMBER OF SERVICES BIOINFORMATICS NUMBER OF SERVICES STATISTICS
Teaching activities (Courses & Personalized) 9 490 40 2 1 1
High Throughput Data Analysis (Bioinformatics) 29 816.8 1 147 33 33
Data Analysis for Clinical Research (Biostatistics) 26 978.8 1 038 85 85
Statistical & methodological consultancy services N/A 309 103 103
Database & applications development (REDCap ) 7 980 307 40 40
Clinical Trials data analysis 10370 399 13 13
Regular Consultancy Collaborations 37 000 1 423 2 2
Budgets for grant proposals 0.0 63 21 7 14
TOTAL 121 635.6 4 725 299 41.0 258

UEB services by user type

TOTAL (€) TOTAL (hours) TOTAL (num services)
Internal 87 970.0 3 383 228
External 24 175.6 778 46
TOTAL 112 145.6 4 161.9 274

ARO (Academic Research Organization)

Active studies by Hospital Service

59TOTAL

Active studies by Hospital Service

Phases of the studies

Phases of the studies
3 | 5.08%PHASE I
4 | 6.78%PHASE I/II
10 | 16.95%PHASE II
15 | 25.42%PHASE III
15 | 25.42%PHASE IV
4 | 6.78%OBSERVATIONAL STUDY
7 | 11.86%OTHER CLINICAL RESEARCH
1 | 1.69%MEDICAL DEVICE

Clinical studies managed through networks

Clinical studies managed through networks
19 | 32.20%SCReN
3 | 5.08%ECRIN
37 | 62.71%OUT OF NETWORKS

Promoter

Promoter
5 | 8.47%MEDICAL SOCIETY
19 | 32.20%VHIR
5 | 8.47%PHARMACEUTICAL LABORATORIES
25 | 42.37%HOSPITAL
3 | 5.08%UNIVERSITY
2 | 3.39%OTHERS

Development area

40NATIONALS
19INTERNATIONALS

Centers participating

18UNICENTRIC
41MULTICENTRIC