Infectious Diseases

Overview

The groups of this area aim to improve the outcomes of patients with infectious diseases. During 2020, we have developed basic, translational and clinical research in the field of the COVID-19 infection, including the virus characterization, the study of the mechanisms of pathogenesis, the diagnosis, the epidemiology, the prevention of the disease and the therapeutics and management options to improve the outcome of the infected people. Additionally, we have continued working on the development of strategies to diagnose, prevent and solve clinical problems related to other infectious diseases and in the characterization of the mechanisms of pathogenicity and antimicrobial resistance of different infectious disease agents. Likewise, we have advanced in the research in critical care and sepsis as well as in aspects related to children’s infectious diseases and primary immunodeficiencies.

Publications

298

total

1734

impact factor

5.82

average impact factor

Group Leader: Ricard Ferrer Roca

team

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SODIR participated in several multicentric studies about coronavirus-2 disease (COVID-19) that lead to several publications. The sepsis research line has participated in studies about the use of new antibiotics for multidrug resistant bacteria. This line is specially interested on the identification of biomarkers for the early diagnosis and stratification of septic patient. The acute respiratory failure research line has two important publications in the field of nasal high flow therapy and weaning from mechanical ventilation.

SODIR has three ongoing funded projects (Health Institute Carlos III) in the area of lung transplantation and hemophagocytic syndrome. The third study analyzes the environmental contamination and aerosol transmission of SARS-CoV-2 in patients treated with nasal high flow.

SODIR is considered as an emerging research group by AGAUR. SODIR also has an important Clinical Research Unit that centralizes all the clinical trials that are carried out in the group.

47

total

512

impact factor

10^.90

average impact factor

SELECTED ARTICLES

Hernández Martínez G, Rodriguez ML, Vaquero MC, Ortiz R, Masclans JR, Roca O, Colinas L, de Pablo R, Espinosa MD, Garcia-de-Acilu M, Climent C, Cuena-Boy R.
High-Flow Oxygen with Capping or Suctioning for Tracheostomy Decannulation.
N Engl J Med. 2020 Sep 10;383(11):1009-1017.
DOI: 10.1056/NEJMoa2010834
IF: 74.699
Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernandez J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kassens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE, Rodriguez-Frias F, Zanella A, Bandera A, Protti A, Aghemo A, Lleo A, Biondi A, Caballero-Garralda A, Gori A, Tanck A, Carreras Nolla A, Latiano A, Fracanzani AL, Peschuck A, Julia A, Pesenti A, Voza A, Jimenez D, Mateos B, Nafria Jimenez B, Quereda C, Paccapelo C, Gassner C, Angelini C, Cea C, Solier A, Pestana D, Muniz-Diaz E, Sandoval E, Paraboschi EM, Navas E, Garcia Sanchez F, Ceriotti F, Martinelli-Boneschi , Peyvandi F, Blasi F, Tellez L, Blanco-Grau A, Hemmrich-Stanisak G, Grasselli G, Costantino G, Cardamone G, Foti G, Aneli S, Kurihara H, ElAbd H, My I, Galvan-Femenia I, Martin J, Erdmann J, Ferrusquia-Acosta J, Garcia-Etxebarria K, Izquierdo-Sanchez L, Bettini LR, Sumoy L, Terranova L, Moreira L, Santoro L, Scudeller L, Mesonero F, Roade L, Ruhlemann MC, Schaefer M, Carrabba M, Riveiro-Barciela M, Figuera Basso ME, Valsecchi MG, Hernandez-Tejero M, Acosta-Herrera M, D’Angio M, Baldini M, Cazzaniga M, Schulzky M, Cecconi M, Wittig M, Ciccarelli M, Rodriguez-Gandia M, Bocciolone M, Miozzo M, Montano N, Braun N, Sacchi N, Martinez N, Ozer O, Palmieri O, Faverio P, Preatoni P, Bonfanti P, Omodei P, Tentorio P, Castro P, Rodrigues PM, Blandino Ortiz A, de Cid R, Ferrer R, Gualtierotti R, Nieto R, Goerg S, Badalamenti S, Marsal S, Matullo G, Pelusi S, Juzenas S, Aliberti S, Monzani V, Moreno V, Wesse T, Lenz TL, Pumarola T, Rimoldi V, Bosari S, Albrecht W, Peter W, Romero-Gomez M, D’Amato M, Duga S, Banales JM, Hov JR, Folseraas T, Valenti L, Franke A, Karlsen TH.
Genomewide Association Study of Severe Covid-19 with Respiratory Failure.
N Engl J Med. 2020 Oct 15;383(16):1522-1534.
DOI: 10.1056/NEJMoa2020283
IF: 74.699
Riera J, Argudo E, Ruiz-Rodríguez JC, Rodríguez-Lecoq R, Ferrer R.
Full neurological recovery 6 h after cardiac arrest due to accidental hypothermia.
Lancet. 2020 May 16;395(10236):e89.
DOI: 10.1016/S0140-6736(20)30751-0
IF: 60.392
Bassetti M, Echols R, Matsunaga Y, Ariyasu M, Doi Y, Ferrer R, Lodise TP, Naas T, Niki Y, Paterson DL, Portsmouth S, Torre-Cisneros J, Toyoizumi K, Wunderink RG, Nagata TD.
Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bacteria (CREDIBLE-CR): a randomised, open-label, multicentre, pathogen-focused, descriptive, phase 3 trial.
Lancet Infect Dis. 2020 Oct 12.
DOI: 10.1016/S1473-3099(20)30796-9
IF: 24.446
Rochwerg B, Einav S, Chaudhuri D, Mancebo J, Mauri T, Helviz Y, Goligher EC, Jaber S, Ricard JD, Rittayamai N, Roca O, Antonelli M, Maggiore SM, Demoule A, Hodgson CL, Mercat A, Wilcox ME, Granton D, Wang D, Azoulay E, Ouanes-Besbes L, Cinnella G, Rauseo M, Carvalho C, Dessap-Mekontso A, Fraser J, Frat JP, Gomersall C, Grasselli G, Hernandez G, Jog S, Pesenti A, Riviello ED, Slutsky AS, Stapleton RD, Talmor D, Thille AW, Brochard L, Burns KEA.
The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline.
Intensive Care Med. 2020 Dec;46(12):2226-2237. Epub 2020 Nov 17.
DOI: 10.1007/s00134-020-06312-y
IF: 17.679

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