Neurotraumatology and Neurosurgery Unit (UNINN) : VHIR Annual Report 2020

Neurosciences

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Overview

The Neuroscience area is consolidating its position as one of the largest clusters of research labs working on neurological diseases across Europe. At present, the area comprises 14 groups with more than one hundred fully dedicated researchers in close contact with top clinicians in the hospital. These research groups pursue a better and multifaceted understanding of the etiopathogenic mechanisms underlying a large variety of mostly adult but also pediatric neurological disorders including stroke, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, primary headaches, epilepsy, neuromuscular disorders, and also neurosurgical and psychiatric pathologies. The area also integrates groups involved in neuroimaging, analysis and interpretation of high-throughput data, and gene therapy strategies to target inflammatory and neurodegenerative neurological conditions.

Publications

316
total
1898
impact factor
6.01
average impact factor

Group Leaders: Joan Sahuquillo Barris and Ma Antonia Poca Pastor

In 2020, several studies have continued in our different research lines, as well as the publication of original articles related with congenital alterations of the craniocervical junction (sleep disorders and morphometric studies of the oropharynx and skull base), pathophysiology of severe TBI-electrical phenomena, pediatric hydrocephalus, normal pressure hydrocephalus in adult patients, and the role of molecular receptors involved in the formation of cerebral edema such as the upregulation sulfonylurea receptor -SUR1- and the pore-forming subunit of KATP -Kir6.2-). In the last case, we studied the pathophysiological mechanisms of brain edema and cell death in malignant brain tumors. This year we have started the organization of a teaching platform aimed at organizing hybrid courses (face-to-face and online) in two of our lines of research (hydrocephalus and neurocritical patient). Additionally, we have remained involved in the ERN CRANIO and in the ERN ITHACA, and have received support from 5 national and European grants (FIS, KidsBrainIT, BitMap, Marató TV3 and AECC).

VHIR Annual Report 2020