Neurosciences

Overview

The Neuroscience area is consolidating its position as one of the largest clusters of research labs working on neurological diseases across Europe. At present, the area comprises 14 groups with more than one hundred fully dedicated researchers in close contact with top clinicians in the hospital. These research groups pursue a better and multifaceted understanding of the etiopathogenic mechanisms underlying a large variety of mostly adult but also pediatric neurological disorders including stroke, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, primary headaches, epilepsy, neuromuscular disorders, and also neurosurgical and psychiatric pathologies. The area also integrates groups involved in neuroimaging, analysis and interpretation of high-throughput data, and gene therapy strategies to target inflammatory and neurodegenerative neurological conditions.

Publications

316

total

1898

impact factor

6.01

average impact factor

Group Leader: Alex Rovira Cañellas

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We have led a study to stablish international consensus recommendations on the use of brain and spinal cord atrophy in multiple sclerosis (MS) that have been published in a high impact journal. We have also led a study in which European and North American experts in the field of MS have been working in providing general recommendations on the use of MRI in diagnosis and monitoring this disease, which have been accepted for publication in Lancet Neurol.

We have also evaluated advanced MRI techniques, such as susceptibility weighted imaging (SWI) to improve the diagnostic accuracy of MS and to differentiate acute from chronic MS lesions. Finally, we have been working on the value of T1/T2 mapping in assessing tissue integrity in MS.

31

total

189

impact factor

6^.11

average impact factor

SELECTED ARTICLES

Tintore M, Arrambide G, Otero-Romero S, Carbonell-Mirabent P, Rio J, Tur C, Comabella M, Nos C, Arevalo MJ, Anglada E, Menendez R, Midaglia L, Galan I, Vidal-Jordana A, Castillo J, Mulero P, Zabalza A, Rodriguez-Acevedo B, Rodriguez M, Espejo C, Sequeira J, Mitjana R, de Barros A, Pareto D, Auger C, Perez-Hoyos S, Sastre-Garriga J, Rovira A, Montalban X.
The long-term outcomes of CIS patients in the Barcelona inception cohort: Looking back to recognize aggressive MS.
Mult Scler. 2020 Nov;26(13):1658-1669.
DOI: 10.1177/1352458519877810
IF: 5.649
Caruana G, Pessini LM, Cannella R, Salvaggio G, de Barros A, Salerno A, Auger C, Rovira A.
Texture analysis in susceptibility-weighted imaging may be useful to differentiate acute from chronic multiple sclerosis lesions.
Eur Radiol. 2020 Nov;30(11):6348-6356.
DOI: 10.1007/s00330-020-06995-3
IF: 4.101
Pareto D, Garcia-Vidal A, Alberich M, Auger C, Montalban X, Tintore M, Sastre-Garriga J, Rovira A.
Ratio of T1-Weighted to T2-Weighted Signal Intensity as a Measure of Tissue Integrity: Comparison with Magnetization Transfer Ratio in Patients with Multiple Sclerosis.
AJNR Am J Neuroradiol. 2020 Mar;41(3):461-463.
DOI: 10.3174/ajnr.A6481
IF: 3.381
Sastre-Garriga J, Pareto D, Battaglini M, Rocca MA, Ciccarelli O, Enzinger C, Wuerfel J, Sormani MP, Barkhof F, Yousry TA, De Stefano N, Tintore M, Filippi M, Gasperini C, Kappos L, Rio J, Frederiksen J, Palace J, Vrenken H, Montalban X, Rovira A.
MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice.
Nat Rev Neurol. 2020 Mar;16(3):171-182. Epub 2020 Feb 24.
DOI: 10.1038/s41582-020-0314-x
IF: 27.000
Clarke MA, Pareto D, Pessini-Ferreira L, Arrambide G, Alberich M, Crescenzo F, Cappelle S, Tintore M, Sastre-Garriga J, Auger C, Montalban X, Evangelou N, Rovira A.
Value of 3T Susceptibility-Weighted Imaging in the Diagnosis of Multiple Sclerosis.
AJNR Am J Neuroradiol. 2020 Jun;41(6):1001-1008.
DOI: 10.3174/ajnr.A6547
IF: 3.381

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