Vascular Biology and Metabolism (VAM)

Overview

The VAM area was created to allow a comprehensive, cooperative and multidisciplinary approach in basic, clinical and epidemiology research. The ultimate goal is the innovation and transfer of solutions in a group of diseases that are closely interrelated and that constitute the leading cause of morbidity and mortality in the world: cardio-cerebrovascular disease, diabetes-metabolic syndrome and renal impairment. The VAM area includes preclinical and clinical research staff from our center, and collaborative work with groups of the highest international prestige. VAM area includes 8 groups: Cardiovascular Pathology, Diabetes and Metabolism, Nephrology, Ophthalmology (focused on retinal vascular disease), CIBBIM-Nanomedicine and Kidney Physiopathology, Medical Molecular Imaging, Neurovascular Diseases, and Research on Aging, Frailty and Transitions in Barcelona. All groups use an integrative tridimensional approach to generate knowledge on the mechanisms of diseases to generate new diagnostic and therapeutic tools.

Publications

281

total

1353

impact factor

4.81

average impact factor

Group Leader: Ignacio Ferreira González

team

group-zoom

zoom

group-download

download

In 2020 we have joined a large multidisciplinary international project on aortic disease (CAMR-AI) using cardiac magnetic resonance imaging, funded by the European Commission (EU EIT Health Grant). Its aim is to advance non-invasive imaging for the personalized management of aortic diseases through an innovative software, so as to decrease mortality, morbidity, and healthcare costs. Another remarkable achievement has been the approval by the European Commission for us to join the European Reference Network in thematic areas 2 and 4 (familial cardiomyopathies and congenital heart disease). Three other projects have been funded by ISC-III and 5 by the Spanish Society of Cardiology. Articles have been published on ischemic heart disease, aorta, arrhythmias and cardiac imaging (4D-Flow in cardiac NMR studies). A new treatment against ischemia-reperfusion injury and adverse myocardial remodeling based on the inhibition of calpains has led to knowledge transfer to industry and society.

117

total

599

impact factor

5^.12

average impact factor

SELECTED ARTICLES

Dux-Santoy L, Guala A, Sotelo J, Uribe S, Teixidó-Turà G, Ruiz-Muñoz A, Hurtado DE, Valente F, Galian-Gay L, Gutiérrez L, González-Alujas T, Johnson KM, Wieben O, Ferreira I, Evangelista A, Rodríguez-Palomares JF.
Low and Oscillatory Wall Shear Stress Is Not Related to Aortic Dilation in Patients With Bicuspid Aortic Valve: A Time-Resolved 3-Dimensional Phase-Contrast Magnetic Resonance Imaging Study.
Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):e10-e20. Epub 2019 Dec 5.
DOI: 10.1161/ATVBAHA.119.313636
IF: 6.604
Ruiz-Meana M, Bou-Teen D, Ferdinandy P, Gyongyosi M, Pesce M, Perrino C, Schulz R, Sluijter JPG, Tocchetti CG, Thum T, Madonna R.
Cardiomyocyte ageing and cardioprotection: consensus document from the ESC working groups cell biology of the heart and myocardial function.
Cardiovasc Res. 2020 Sep 1;116(11):1835-1849
DOI: 10.1093/cvr/cvaa132
IF: 8.168
Marcos-Garces V, Gavara J, Lopez-Lereu MP, Monmeneu JV, Rios-Navarro C, de Dios E, Perez N, Cànoves J, Gonzalez J, Minana G, Nunez J, de la Espriella R, Santas E, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Rodríguez-Palomares JF, Ortiz-Pérez JT, Bodi V.
Ejection Fraction by Echocardiography for a Selective Use of Magnetic Resonance After Infarction.
Circ Cardiovasc Imaging. 2020 Dec;13(12):e011491. Epub 2020 Dec 10.
DOI: 10.1161/CIRCIMAGING.120.011491
IF: 5.691
Ruiz-Meana M, Boengler K, Garcia-Dorado D, Hausenloy DJ, Kaambre T, Kararigas G, Perrino C, Schulz R, Ytrehus K.
Ageing, sex, and cardioprotection.
Br J Pharmacol. 2020 Dec;177(23):5270-5286 Epub 2020 Feb 3.
DOI: 10.1111/bph.14951
IF: 7.730
Muntané-Carol G, Urena M, Munoz-Garcia A, Padrón R, Gutiérrez E, Regueiro A, Serra V, Capretti G, Himbert D, Moris C, Sabaté M, Garcia Del Blanco B, Ferreira-Neto AN, Coté M, Fischer Q, Couture T, Kalavrouziotis D, Rodés-Cabau J.
Late Cerebrovascular Events Following Transcatheter Aortic Valve Replacement.
JACC Cardiovasc Interv. 2020 Apr 13;13(7):872-881. Epub 2020 Mar 11.
DOI: 10.1016/j.jcin.2019.11.022
IF: 8.432

View all publications